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PERIO - Periodontal Practice Today
PERIO - Periodontal Practice Today 5 (2008), No. 3     18. Nov. 2008
PERIO - Periodontal Practice Today 5 (2008), No. 3  (18.11.2008)

Page 169-177

Periodontal treatment in two siblings with Papillon-Lefèvre syndrome: 12-year follow-up and review of the literature
Vrahopoulos, Theofilos P. / Grous, Alexandros
Aim: The aim of this report was to present the periodontal treatment and maintenance over a period of 12 years in two siblings with Papillon-Lefèvre syndrome (PLS), aged 17 and 15 years respectively.
Study design: Initial treatment included oral hygiene instructions, a 0.12% chlorhexidine digluconate mouthrinse and scaling and root planing with simultaneous administration of oral 250 mg tetracycline twice daily for 2 weeks. For the first 4 years, patients were enrolled in a 1-month recall maintenance programme. Due to re-establishment of inflammation, during the next 8 years combined mechanical and antimicrobial periodontal therapy was administered. Clinical and radiographic evaluation was performed in 1993, 1996, 2000 and 2004.
Results: In the first period, periodontal disease activity was controlled. In the second period, periodontal breakdown advanced rapidly, especially in the younger sibling. Tooth loss was inevitable, and both patients became edentulous at the age of 29 and 27 respectively.
Conclusions: The role of oral hygiene in PLS may determine the rate of disease advance on an individual basis. As evidenced in the present cases, the adoption of a strict maintenance schedule and a high level of oral hygiene efficacy is a prerequisite for prolonging the life of the dentition.

Keywords: maintenance, oral hygiene, Papillon-Lefèvre syndrome, periodontal treatment, periodontitis, recurrence, tooth loss