Proliferative verrucous leuoplakia (PVL) is widely accepted as an aggressive variant of oral leukoplakia, which tends to manifest itself as a longstanding, persistent leukoplakia that is typically resistant to treatment. Although the aetiology of PVL is unknown, the potential for recurrence and malignant transformation is such that treatment of this lesion requires an aggressive approach. Even with this approach, reports suggest that affected patients are at risk of developing verrucous or oral squamous cell carcinoma during episodes of recalcitrant disease. This report describes the clinical presentation of a patient with PVL. It outlines the difficulties in treatment planning for patients with the condition and discusses the long-term implications of such a diagnosis.
Keywords: aggressive, gingivae, management, proliferative verrucous leukoplakia (PVL)