PERIO - Periodontal Practice Today
PERIO - Periodontal Practice Today 1 (2004), No. 1     7. May 2004
PERIO - Periodontal Practice Today 1 (2004), No. 1  (07.05.2004)

Page 5-15


Biomaterials for the Reconstructive Treatment of Periodontal Intrabony Defects.
Part I. Bone Grafts and Bone Substitutes
Sculean, Anton/Jepsen, Søren
The aim of the paper is to present a critical overview, with emphasis on the evidence from human histology, on the different types of bone grafts and bone substitutes used in regenerative periodontal therapy of intraosseous defects. The available evidence indicates that surgical periodontal therapy employing the use of autogenous bone, demineralized freeze dried bone allograft, bovine bone derived xenografts, may result in periodontal regeneration. At present there is no evidence from human histological studies demonstrating predictable periodontal regeneration following the use of alloplastic (synthetic) materials.

Keywords: periodontal regeneration, human histology, controlled clinical studies, bone grafts, bone substitutes, review