PERIO - Periodontal Practice Today
PERIO - Periodontal Practice Today 5 (2008), No. 4     4. June 2009
PERIO - Periodontal Practice Today 5 (2008), No. 4  (04.06.2009)

Page 259-269


Systemic azithromycin in the treatment of chronic periodontitis that persisted after non-surgical therapy. A report of two cases
Parrish, Lawrence / Mattson, John / Miyamoto, Takanari / Cerutis, D. Roselyn
Chronic periodontitis is a bacteria-induced inflammatory process that results in signs of inflammation, including bleeding-on-probing and deepening probing depths. Treatment usually consists of oral hygiene instruction, root planing and possibly surgery. The present two case reports illustrate the use of the antibiotic azithromycin in the treatment of chronic periodontitis that persisted after scaling and root planing. In these cases, after re-evaluation at the completion of scaling and root planing, the patients elected not to have surgery, and instead decided to receive a course of azithromycin. The data demonstrated improvements in the signs of periodontal inflammation, and these improvements remained during several cycles of maintenance.

Keywords: antibiotics, non-surgical periodontal therapy, periodontitis