PERIO - Periodontal Practice Today
PERIO - Periodontal Practice Today 5 (2008), No. 4     4. June 2009
PERIO - Periodontal Practice Today 4 (2007), No. 4  (19.12.2007)

Page 287-293


A case history of a kidney transplant patient with ciclosporin-induced gingival overgrowth combined with chronic periodontitis
Gera, Istvan / Keglevich, Tibor
The exact patho-mechanisms of ciclosporin-induced gingival overgrowth remain unclear. Gingival hyperplasia is more severe in areas where local irritants such as plaque, calculus and defective restorations are present, although the role of dental plaque in the course of ciclosporin-induced gingival overgrowth is a matter of debate. A clinical case of a middle-aged kidney-transplanted woman is presented in which the gingival overgrowth was successfully eliminated by initial therapy and minimally invasive gingival corrective surgery. The patient's oral hygiene and periodontal health have been successfully controlled by regular supportive therapy for over 9 years.

Keywords: ciclosporin A, gingival overgrowth, kidney transplantation, periodontal supportive therapy, side effects