PERIO - Periodontal Practice Today
PERIO - Periodontal Practice Today 4 (2007), No. 2     13. June 2007
PERIO - Periodontal Practice Today 4 (2007), No. 2  (13.06.2007)

Page 109-113


Gingival enlargement originating from medication and tooth migration
Duffau, Frédéric
Gingival enlargement can be a side effect of medication, including cyclosporin A, phenytoin and calcium channel blockers. This articles discusses the mechanisms involved in gingival enlargement, illustrated with a case report. A 64-year-old female patient presented with tooth migration and gingival swelling. History revealed a previously similar situation after an increase in her dosage of Amlor®, a calcium inhibitor she had been prescribed for hypertension. The diagnosis was generalised chronic periodontitis associated with a gingival enlargement of medicinal origin. After treatment, the misaligned teeth spontaneously returned to alignment. The case illustrates that gingival enlargement can act not only as a bacterial trap, but also as a lever to move teeth.

Keywords: drug-induced gingival enlargement, gingival enlargement, medication, tooth migration