PERIO - Periodontal Practice Today 2 (2005), No. 1 11. Apr. 2005
Necrotizing gingivitis (NG) and necrotizing periodontitis (NP) are considered to be different clinical stages of the same disease process and may be the first clinical indicators of human immunodeficiency virus (HIV) infection. NG/NP is a disease with distinctive clinical manifestations that respond to an uncomplicated regime of treatment. The clinical signs and symptoms of NG in HIVpositive patients are identical to those in HIV-negative patients, and the microflora is the same in either case. In contrast to the reported important role of smoking in NG/NP and periodontal disease in general, smoking does not seem to play a contributory role in the pathogenesis of NG/NP in HIV-positive patients. The lesions of NG/NP tend to affect predominantly the upper and lower anterior periodontal segments, and recurrence after treatment is not common.
Keywords: necrotizing ulcerative gingivitis, necrotizing gingivitis, human immunodeficiency virus